An efficient microwave-assisted enzyme-catalyzed regioselective synthesis of long chain acylated derivatives of flavonoid glycosides

Our present investigation provides a facile, efficient, and economical method of microwave-assisted biocatalytic regioselective synthesis of long chain acylated derivatives of isoquercitrin and phloridzin. (i) Acetone, 3 Å molecular sieves, Novozyme 435®, 45 °C; (ii) R = Oleic, Stearic, Linoleic, Linolenic, Eicosapentaenoic (EPA), Docosahexaenoic Acids (DHA), or their corresponding esters.