Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5264593 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
An efficient and convenient one-pot synthesis of indene derivatives was achieved in moderate to high yields by the CF3SO3H promoted coupling/cyclization reaction of benzylic alcohols and 1,3-dicarbonyls for the first time. For the reactions of methoxy- or methyl-substituted diarylmethanols with 1,3-dicarbonyls, 2Â equiv of CF3SO3H was needed to reach the best results; but for the reactions of methoxy-substituted arylethanols with 1,3-dicarbonyls, 0.6Â equiv of CF3SO3H at lower temperatures was capable of promoting the reaction finished.
Related Topics
Physical Sciences and Engineering
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Organic Chemistry
Authors
Wenxue Zhang, Yisi Dai, Haizhen Zhu, Wei Zhang,