Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5264655 | Tetrahedron Letters | 2014 | 13 Pages |
Abstract
An environment friendly continuous-flow protocol for the Suzuki coupling of boronic acids and aryl halides under ligand-free conditions using solid-supported Pd is presented. The process described herein uses very simple reaction conditions and equipment setup and can be readily scaled up to provide multigram quantities of products containing low levels of residual Pd.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Carlos Mateos, Juan A. Rincón, Beatriz MartÃn-Hidalgo, José Villanueva,