Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5264695 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
Azines, pyrazoles, and pyridazinones were isolated as the sole products in high yields (>97%) by grinding solid hydrazine (H3N+NHCO2â) with di-carbonyl compounds or by their reaction in the absence of solvent. Neither catalysts nor additives were needed to promote the reactions. The solid-state and solvent-free reactions proceeded under ambient conditions and did not produce any wastes other than water and carbon dioxide. They are operationally easy, environmentally safe, and readily scalable, allowing for highly selective synthesis of compounds containing the hydrazine motif.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Byeongno Lee, Philjun Kang, Kyu Hyung Lee, Jaeheung Cho, Wonwoo Nam, Won Koo Lee, Nam Hwi Hur,