Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5264721 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
New pyrrolo[1,2-a]benzimidazole and pyrrolo[1,2-a]quinoxaline derivatives are obtained via one-pot, three-component reactions from 1-benzylbenzimidazoles, α-bromocarbonyl compounds, and non-symmetrical activated acetylenic dipolarophiles in propylene oxide as both the reaction medium and acid scavenger, at room temperature. When the same reaction is performed in 1,2-epoxybutane at reflux temperature only the pyrrolo[1,2-a]benzimidazole derivative is obtained.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Alina Nicolescu, Calin Deleanu, Emilian Georgescu, Florentina Georgescu, Ana-Maria Iurascu, Sergiu Shova, Petru Filip,