Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5264787 | Tetrahedron Letters | 2014 | 4 Pages |
Abstract
Optically active cobalt(II) salen complexes were found to be effective Lewis acid catalysts for the enantioselective Michael addition of O-alkylhydroxylamines to nitroalkenes to afford the corresponding N-alkylhydroxyl-1,2-nitroamines in high yields and with good to high enantioselectivities. This study represents the first example of a transition-metal-catalyzed asymmetric Michael addition of amines to nitroalkenes.
Related Topics
Physical Sciences and Engineering
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Authors
Takumi Kobayashi, Tatsuki Shimura, Yuzuru Kurita, Yoshitaka Katsumata, Satoko Kezuka,