Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5264866 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
A facile one-pot method is reported for the synthesis of 4-alkoxy-2-aminothiophene-3-carbonitriles. Transesterification of trimethylorthoacetate technique allowed introducing alkoxy substituents into 2-aminothiophene ring system. Diverse alkoxy substituents could be introduced efficiently by using this methodology. Further the synthesis of some of new 4-alkylamino-2-aminothiophenes is also reported.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
K. Venkata Rao, C. Balakumar, B. Lakshmi Narayana, D. Pran Kishore, K. Rajwinder, A. Raghuram Rao,