Article ID Journal Published Year Pages File Type
5265090 Tetrahedron Letters 2013 5 Pages PDF
Abstract
The host-guest complex of a proline-thiourea bipyridine trifluoromethanesulfonic acid salt can catalyze organocatalytic asymmetric reactions such as aldol, Michael, and Mannich in polar protic medium with high stereoselectivities. The privileged bipyridine backbone and the thiourea motif are essential to the activity and enantioselectivity through hydrogen bonding interactions.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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