| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5265209 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
Microwave-assisted total syntheses of the highly selective V600EBRAF inhibitors PLX4720 and PLX4032 are reported. In addition to the synthesis of the title compounds, this protocol could enable the development of focused libraries of other novel BRAF-selective compounds.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Jason R. Buck, Sam Saleh, Md. Imam Uddin, H. Charles Manning,