Article ID Journal Published Year Pages File Type
5265232 Tetrahedron Letters 2012 5 Pages PDF
Abstract
The efficient synthesis of 2-arylindoles and 6H-isoindolo[2,1-a]indol-6-one through copper catalysed domino sp-sp2 decarboxylative cross-coupling and subsequent cyclisation reactions of arylpropiolic acids with 2-iodotrifluoroacetanilide has been described. This methodology also demonstrates that indolo[1,2-c]quinazolin-6(5H)-one can be obtained with the elimination of trifluoromethyl anion.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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