Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5265252 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
An environmentally benign and operationally simple methodology was developed for the regio- and stereoselective synthesis of (Z)-3-methyleneisoindolinones in aqueous micellar medium from 2-iodo-N-phenyl-benzamides and terminal alkyne by Cu-free domino Sonogashira reaction followed by 5-exo-dig-cyclization using Pd(CH3CN)Cl2 as catalyst and 1,4-bis(4-pyridyl)-2,3-diaza-1,3-butadiene as ligand under aerobic condition.
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Authors
Swarbhanu Sarkar, Samrat Dutta, Rajdip Dey, Subhendu Naskar,