| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5265282 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
A palladium-catalysed, silane-mediated hydrodehalogenation (HDH) reaction with increased substrate scope has been developed. Whereas previous attempts to reduce carboxylic acid or phenol-containing aryl halides using silane-based HDH conditions failed, the current protocol allows efficient access to the reduced products. Chemoselective HDH in the presence of sensitive functional groups is also presented.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Gary M. Noonan, Barry R. Hayter, Andrew D. Campbell, Timothy W. Gorman, Benjamin E. Partridge, Gill M. Lamont,