Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5265342 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
A highly efficient one-pot synthesis of 5,6-disubstituted-5H-pyrrolo[2,3-b]pyrazine-2,3-dicarbonitriles is presented. The reaction of 5-(alkyl-arylamino)-6-chloropyrazine-2,3-dicarbonitriles with phenylacetylene, catalyzed by Pd-Cu, in the presence of SDS as the surfactant in water, leads to the desired products in good-to-high yields.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ali Keivanloo, Mohammad Bakherad, Hossein Nasr-Isfahani, Somayeh Esmaily,