Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5265422 | Tetrahedron Letters | 2013 | 8 Pages |
Abstract
A libraries from libraries approach is described for the synthesis of five different sulfonamide linked scaffolds. Four of the scaffolds are sulfonamides linked to heterocycles; piperazine, thiourea, cyclic guanidine, and dimethyl cyclic guanidine. The fifth scaffold is a polyamine linked sulfonamide. Three different diversity positions were effectively incorporated into each scaffold providing a number of different compounds with good yields and purity.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Ginamarie Debevec, Wenteng Chen, Yongping Yu, Richard A. Houghten, Marc A. Giulianotti,