| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5265426 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
Hydroaroylation of methyl acrylate 2a to give the α-aroyl esters 4 took place in the three-component reaction of 2a, aroyl chlorides 1, and Et2MeSiH in the presence of 1 mol % of [Rh(cod)(PR3)2]OTf (cod = 1,5-cyclooctadiene, OTf = OSO2CF3, R = Ph (3a), OPh (3b)) in CH2Cl2. GC and 1H NMR investigation revealed that the rhodium-catalyzed hydroaroylation proceeds via two successive transformations, that is, hydrosilylation of 2a to afford silyl enol ether 5a followed by C-C bond formation between 5a and 1a.
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Authors
Takako Muraoka, Eiji Hiraiwa, Minami Abe, Keiji Ueno,