| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5265449 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
A general method for the synthesis of triazoles containing selenium and tellurium was accomplished via a CuCAAC reaction between organic azides and a terminal triple bond, generated by in situ deprotection of the silyl group. The reaction tolerates alkyl and arylazides, with alkyl and aryl substituents directly bonded to the chalcogen atom. The products were readily functionalized by a nickel-catalyzed Negishi cross-coupling reaction, furnishing the aryl-heteroaryl products at the 4-position in good yields.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hélio A. Stefani, Daiana M. Leal, Flávia Manarin,