| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5265519 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
This Letter describes a novel three step solution phase protocol to synthesize 3-(tetrazol-5-yl)quinoxalin-2(1H)-ones that utilizes the Ugi-Azide MCR followed by cyclization under acidic condition and immediate oxidation with TEMPO/CAN. The method was also expanded to produce a bis-benzodiazepine tetrazole.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Steven Gunawan, Gary Nichol, Christopher Hulme,