| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5265586 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
Four new highly oxygenated xanthones, named muchimangins A-D (1-4), with a diphenylmethyl substituent have been isolated as extremely minor constituents from the root of Securidaca longepedunculata (Polygalaceae). Among them, muchimangin B (2) induced an apoptotic-like cell death of human pancreatic cancer PANC-1 cell line preferentially in nutrient deprived condition with PC50 of 38.9 μM.
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Authors
Dya Fita Dibwe, Suresh Awale, Shigetoshi Kadota, Yasuhiro Tezuka,