Article ID Journal Published Year Pages File Type
5265638 Tetrahedron Letters 2013 4 Pages PDF
Abstract
A variety of aldehydes undergo a smooth coupling with 6-methylhept-5-en-2ol in the presence of molecular iodine to afford the 2,3,6-trisubstituted tetrahydropyrans in good yields through 3,5-oxonium-ene cyclization under mild and neutral conditions. This method is simple, convenient, and cost-effective.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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