Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5265653 | Tetrahedron Letters | 2013 | 5 Pages |
Abstract
An attempted Sonogashira reaction of 2-nitroiodobenzene and phenyl acetylene catalyzed by Pd(PPh3)4/Cu in water in the presence of pyrrolidine proceeds with simultaneous regioselective hydration of the Sonogashira alkyne leading to the corresponding aryl ketone. A series of functionalized 2-(2-nitrophenyl)-1-aryl ethanones are obtained in high yields by this procedure.
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Authors
Sabir Ahammed, Raju Dey, Brindaban C. Ranu,