| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5265999 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
The large scale synthesis of functionalized 2-pyridylboronate 8 and optimization of its Suzuki-Miyaura coupling to chloropyrazoline (R)-7 to provide a scalable synthesis of mineralocorticoid antagonist (R)-1 is described.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Charles Boos, Daniel M. Bowles, Cuiman Cai, Agustin Casimiro-Garcia, Xiangyang Chen, Catherine A. Hulford, Sandra M. Jennings, E. Jason Kiser, David W. Piotrowski, Matthew Sammons, Robert A. Wade,