| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5266018 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A new, one-pot, four-component condensation of 3-methyl-1H-pyrazol-5(4H)-one, ammonium acetate, aromatic aldehydes, and meldrum's acid in [bmim]BF4 as solvent is described for the synthesis of 3-(5-amino-3-methyl-1H-pyrazol-4-yl)-3-arylpropanoic acid derivatives. This methodology resulting in excellent isolated yields in short reaction time is characterized by simple work up procedure and little environmental impact.
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Authors
Zhiyong Xiao, Min Lei, Lihong Hu,