Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5266091 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
Acid-catalysed cyclisations of the 2-aminoethyl styrene derivatives 9 give good to excellent yields of the corresponding tetrahydroisoquinolines 7 by an intramolecular hydroamination reaction, which represents an alternative and potentially more flexible strategy to the classical Pictet-Spengler method for the syntheses of such heterocycles.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Laura Henderson, David W. Knight, Andrew C. Williams,