Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5266167 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Two efficient syntheses of 1,4-benzothiazepines, substituted in the positions 2 and 5, have been achieved either by a ring expansion reaction of cyclic sulfenamides with methylpropiolate or tosylacetylene catalyzed by pyridine, via a postulated allenolate intermediate; or by an α-sulfenylation reaction promoted by diethylamine and a subsequent acid catalyzed condensation reaction.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Cédric Spitz, Vincent Reboul, Patrick Metzner,