Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5266179 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Radicamine B 5 was synthesized from p-hydroxy benzaldehyde 7 stereoselectively using acid catalysed amido cyclisation with the help of neighbouring group participation (NGP). Without NGP both radicamine B 5 and its epimer 5-epi radicamine B 6 were obtained. The key steps of the synthesis are Sharpless asymmetric dihydroxylations and acid mediated amido cyclisation.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Y. Jagadeesh, B. Venkateswara Rao,