Article ID Journal Published Year Pages File Type
5266296 Tetrahedron Letters 2012 4 Pages PDF
Abstract
A divergent strategy for the synthesis of 1-aryl- and 2-aryl-2-iminoimidazolidines is presented. Cyclization of N-Boc-N′-aryl-N′′-(2-hydroxyethyl)guanidines in the presence of methanesulfonyl chloride and triethylamine or sodium hydride at 0 °C affords the corresponding 2-iminoimidazolidines in good yields.
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Physical Sciences and Engineering Chemistry Organic Chemistry
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