| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5266308 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
PEGylated core-shell type resin (PEG-AM SURE) was developed by modifying the surface of AM SURE⢠resin with diamino PEG. The conditions for the PEG coupling reaction were optimized by adjusting PEG chain cross-linking and the amount of free amino groups to ensure a enough loading level of functional groups on the resin (>0.30-0.39 mmol NH2/g). The resulting PEG-AM SURE resin showed better performance than conventional resins during solid-phase peptide synthesis of JR10-mer and β2m58-69 12-mer.
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Authors
Mira Kim, Yong-Sun Park, Dong-Sik Shin, Song Lee, Yoon-Sik Lee,