Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5266510 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
Asymmetric total synthesis of a dihydroisocoumarin, (3R,4R)-(â)-6-methoxy-1-oxo-3-pentyl-3,4-dihydro-1H-isochromen-4-yl acetate (1) starting from commercially available m-anisic acid is described. Herein, we depict the use of protective opening of lactones and construction of δ lactone. The synthesis involves Wittig, Grubbs cross metathesis, and Sharpless dihydroxylation reactions.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
D. Chanti Babu, Ch. Bhujanga Rao, D. Ramesh, S. Raghavendra Swamy, Y. Venkateswarlu,