| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5266512 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
Mekongenine A (1) possessing an unprecedented structure constituted from the union of a rare 2,7-seco eburnamine half and an aspidospermine alkaloid, together with a new bisindole alkaloid, mekongenine B (2), consisting of an eburnamine-aspidospermine type skeleton, was isolated from Bousigonia mekongensis. Their structures were elucidated by means of spectroscopic methods and those of 2 were further confirmed by X-ray diffraction. The absolute configurations of 1 and 2 were determined by comparison of quantum chemical TDDFT calculated and experimental ECD spectra. Mekongenines A (1) and B (2) exhibited cell growth inhibitory activities against various human cancer cell lines.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Yanhui Fu, Hongping He, Yingtong Di, Shunlin Li, Yu Zhang, Xiaojiang Hao,