| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5266576 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
The diastereoselective substitution of 3-bromolactam derived from (R)-(â)-2-phenylglycinol with a variety of arylcuprate reagents is presented. The stereochemical outcome of the substitution reaction is discussed. The method provides an efficient and straightforward route to enantiopure 3-arylpiperidines.
Related Topics
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Authors
Oscar Romero, Alejandro Castro, Joel L. Terán, Dino Gnecco, MarÃa L. Orea, Ángel Mendoza, Marcos Flores, Luis F. Roa, Jorge R. Juárez,