Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5266599 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
A new method for pre-activation of N-acetyl-5-N,4-O-carbonyl-protected p-tolyl thiosialoside donor with AgOTf and p-toluenesulfenyl chloride followed by coupling with other p-tolyl thioglycosides is reported. Excellent α-sialylation yields were achieved for these coupling reactions, as high as 91% yield of only α-isomer.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Bin Sun, Heyan Jiang,