Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5266612 | Tetrahedron Letters | 2013 | 4 Pages |
Abstract
The first asymmetric reduction of ketimines with catecholborane employing an enantiopure N-triflyl phosphoramide as the organocatalyst has been developed. Five mole % of the catalyst provides the corresponding secondary amines in very good to almost quantitative yields and good enantioselectivities up to 86:14 e.r. under mild reaction conditions.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Dieter Enders, Andreas Rembiak, Matthias Seppelt,