Article ID Journal Published Year Pages File Type
5266612 Tetrahedron Letters 2013 4 Pages PDF
Abstract
The first asymmetric reduction of ketimines with catecholborane employing an enantiopure N-triflyl phosphoramide as the organocatalyst has been developed. Five mole % of the catalyst provides the corresponding secondary amines in very good to almost quantitative yields and good enantioselectivities up to 86:14 e.r. under mild reaction conditions.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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