Article ID Journal Published Year Pages File Type
5266804 Tetrahedron Letters 2012 5 Pages PDF
Abstract
This work describes a green and efficient one-pot synthesis of N-alkyl-2-(2-oxoazepan-1-yl)-2-arylacetamide derivatives via an Ugi four-center, three-component reaction of 6-aminohexanoic acid, aromatic aldehydes, and isocyanide derivatives in water under reflux conditions in the absence of a catalyst.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
Authors
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