Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5266816 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
A concise and efficient approach to a series of chromen-4-ones with fused thiophene ring has been developed using the Suzuki-Miyaura reaction of bromothiophene-2- and 3-carboxylates with 2-methoxyboronic acids and subsequent cyclization of prepared alkyl (2-methoxy)aryl thiophene-2- and 3-carboxylates under the action of BBr3/KOtBu. Starting bromothiophenes are easily obtained from corresponding commercially available aminothiophenes by diazotization/bromination reaction.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Viktor O. Iaroshenko, Sajid Ali, Satenik Mkrtchyan, Ashot Gevorgyan, Tariq Mahmood Babar, Volodymyr Semeniuchenko, Zahid Hassan, Alexander Villinger, Peter Langer,