Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5266873 | Tetrahedron Letters | 2012 | 5 Pages |
Abstract
1,3-Dipolar cycloaddition of a chiral nitrone derived from (â)-menthone to (E)-1,4-dichlorobut-2-ene was the key step in a novel 5 step synthesis of (2S,3S,4R)-4-hydroxyisoleucine, obtained in 21% overall yield with high enantiopurity.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kaïss Aouadi, Erwann Jeanneau, Moncef Msaddek, Jean-Pierre Praly,