| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5266882 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
The presented experimental work investigates the usefulness of temporary monoprotection of symmetrical terminal diynes in the coupling with aryl iodides. The monoprotection/cross-coupling/deprotection approach proved to be efficient for the coupling of diynes with aryl substrates avoiding the formation of diarylated byproducts. The high importance of the ratio of solvents in the Sonogashira coupling is demonstrated.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Karolin Kral, Marko Hapke,