Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5266960 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
A new method for the synthesis of trifluoromethylated acetylenes is developed which involves the copper-catalyzed trifluoromethylation of alkynyltrifluoroborates with an electrophilic trifluoromethylating reagent. This method offers significant advantages such as efficiency and mild and base-free reaction conditions. A plausible mechanism is proposed.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Huidong Zheng, Yuanyuan Huang, Zhiwei Wang, Huaifeng Li, Kuo-Wei Huang, Yaofeng Yuan, Zhiqiang Weng,