Article ID Journal Published Year Pages File Type
5266991 Tetrahedron Letters 2011 4 Pages PDF
Abstract
tert-Butyl methyl ether (TBME) has been effectively used as a reagent for esterification of carboxylic acids. By varying amounts of sulfuric acid, a remarkable regioselectivity in esterification has been demonstrated. Additionally, under the present reaction conditions, one-pot esterification and Ritter reaction are achieved in almost quantitative yield.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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