Article ID Journal Published Year Pages File Type
5267108 Tetrahedron Letters 2012 4 Pages PDF
Abstract
In this Letter, we report a novel solid-phase strategy using a backbone amide linker (BAL) attached to a polystyrene support for the synthesis of C-terminal agmatine dipeptides. Our method eliminates the need to purify intermediates by column chromatography and enables us to build rapidly an 18-member library of C-terminal agmatine dipeptides which are subsequently screened for inhibitory activity against a viral enzyme.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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