Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5267375 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
A short and efficient Julia-Kocienski olefination protocol, based upon the use of chelating agents (18-crown-6 or TDA-1 for K+; 12-crown-4 or HMPA for Li+), was developed. This protocol enhances the (E)-selectivity of the reaction and the desired olefins are obtained generally with >10:1 (E/Z)-selectivity.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
JiÅà PospÃÅ¡il,