| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5267433 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
We describe the development of an N-heterocyclic carbene catalysed homoenolate addition to 4-nitro-5-styrylisoxazoles to give substituted cyclopentanones with a unique substitution pattern and as single diastereoisomers. The synthetic utility of the cyclopentanones obtained was briefly explored through their conversion into α-fluorinated diketones and keto acids.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Diana Salazar Illera, Surisetti Suresh, Maria Moccia, Gea Bellini, Michele Saviano, Mauro F.A. Adamo,