| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5267569 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Benzamides with tethered acetal groups undergo reactions in CF3SO3H to give ring-fused isoindolinones by a cyclization cascade. The reaction initially forms an N-acyliminium ion which then gives the isoindolinone by the aza-Nazarov reaction. An unusual variant also cyclizes at the allylic position.
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Kiran Kumar Solingapuram Sai, Matthew J. O'Connor, Douglas A. Klumpp,