Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5267570 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
We describe herein our progress toward the synthesis of halicyclamine A, which possesses very interesting biological activities and has never been synthesized. For this purpose, we proposed a stereoselective Diels-Alder reaction as a key step for the establishment of the stereogenic triad of the bis(piperidinyl) core of this molecule. A series of NMR studies was then conducted to establish the correct stereochemical assignment subsequent to the Diels-Alder reaction.
Related Topics
Physical Sciences and Engineering
Chemistry
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Authors
Gary A. Molander, Frédéric Cadoret,