Article ID Journal Published Year Pages File Type
5267706 Tetrahedron Letters 2012 4 Pages PDF
Abstract
An efficient procedure for asymmetric Michael addition reaction of cyclic ketones with low activated chalcones catalyzed by pyrrolidine-based phthalimide and 1,8-Naphthalimide catalysts was developed. The corresponding products were obtained in high yields with high diastereoselectivities (up to 99:1 dr) and high enantioselectivities (up to 96% ee) under mild conditions.
Related Topics
Physical Sciences and Engineering Chemistry Organic Chemistry
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