Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5267706 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
An efficient procedure for asymmetric Michael addition reaction of cyclic ketones with low activated chalcones catalyzed by pyrrolidine-based phthalimide and 1,8-Naphthalimide catalysts was developed. The corresponding products were obtained in high yields with high diastereoselectivities (up to 99:1 dr) and high enantioselectivities (up to 96% ee) under mild conditions.
Related Topics
Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Hong-Yu Xie, Shu-Rong Ban, Ju-Na Liu, Qing-Shan Li,