Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5267937 | Tetrahedron Letters | 2015 | 4 Pages |
Abstract
The synthesis of 4-phenacylidene flavenes (3) was accomplished by a one-pot pseudo three-component condensation reaction between salicylaldehydes and acetophenones in the presence of 20 mol % of bromodimethylsulfonium bromide (BDMS) in acetonitrile at room temperature. The attractive features of this protocol are: use of organo-catalyst BDMS, simple reaction procedure, high bond-forming efficiency, good yields, and environmentally benign reaction conditions.
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