| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5268008 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
An efficient method for the cleavage of the p-methoxybenzyl protecting group of several alcohols in the presence of 0.5Â equiv of trifluoromethanesulfonic acid and 1,3-dimethoxybenzene in dichloromethane at room temperature is described.
Graphical abstractTriflic acid and 1,3-dimethoxybenzene in dichloromethane readily cleaves p-methoxybenzyl (PMB) ethers at room temperature, for example, 13 affords 14 in 98% yield.Download full-size image
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Physical Sciences and Engineering
Chemistry
Organic Chemistry
Authors
Michael E. Jung, Pierre Koch,