Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268029 | Tetrahedron Letters | 2011 | 5 Pages |
Abstract
The efficient organocatalytic cascade approach toward medicinally privileged 2-amino-4H-chromene-3-carbonitriles scaffold is reported. The enantioselective synthesis of these compounds was achieved in high yields and good to high ee values (up to 96% yield and 89% ee) using bifunctional amine-thiourea organocatalysts developed from our laboratory.
Related Topics
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Authors
Zhiyun Du, Woon-Yew Siau, Jian Wang,