| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5268036 | Tetrahedron Letters | 2011 | 4 Pages |
Abstract
Synthesis of new iboga-analogues, replacing the indole ring with a benzofuran moiety has been described. Starting materials are the suitably substituted benzofuran derivatives and have been synthesized by Pd-catalyzed reactions. The conversion of endo-6-methylcarboxylate substituted dehydroisoquinuclidine to exo-isomer, a key component of iboga-alkaloids has been achieved in the presence of NaOMe in methanol under reflux conditions.
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