Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5268063 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
A tandem reaction consisting of five membered-ring selective Prins cyclization and subsequent Friedel-Crafts cyclization was developed. The reactions of phenyl homoallylic alcohol 3 and benzaldehyde derivatives 6 afforded tetrahydroindenofurans 7 or pentacyclic products 8, depending upon the quantity of 6. Also homoallylic alcohol 12 having an alkyne-cobalt moiety reacted with 6 to give rise to tetrahydroindenofurans 13 in good yields.
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Authors
Yuji Suzuki, Takanori Niwa, Eiko Yasui, Megumi Mizukami, Masaaki Miyashita, Shinji Nagumo,