| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5268081 | Tetrahedron Letters | 2012 | 4 Pages |
Abstract
A general, mild and an efficient protocol, which makes use of T3P as an acid activator for the synthesis of Nα-protected amino/peptide thioacids from corresponding acids in the presence of finely ground Na2S as hydrosulfide ion donor is described. The protocol employed significantly increases the overall efficiency as the yield, reaction duration, and purity of even sterically hindered amino acids are concerned.
Related Topics
Physical Sciences and Engineering
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Authors
Chilakapati Madhu, Basavaprabhu Basavaprabhu, T.M. Vishwanatha, Vommina V. Sureshbabu,